Medicine Articles

Authors: Dhiya Moorthy & Sanchi Verma Mentor: Dr. Liam Barrett. Dr. Barrett received his medical degree from the University of Birmingham. He is a member of the Royal College of Emergency Medicine, and is currently pursuing a DPhil in medical science at the University of Oxford. Abstract Crohn’s disease is a long-term inflammatory bowel disease that can affect any part of the gastrointestinal tract. It matters because it causes pain, diarrhea, fatigue, weight loss, and compli

Authors: Annabella Irani-Fey, Tripura Reddy, & Rihaan Shah Mentor: Dr. Liam Barrett. Dr. Barrett received his medical degree from the University of Birmingham. He is a member of the Royal College of Emergency Medicine, and is currently pursuing a DPhil in medical science at the University of Oxford. Abstract This review explores a simple question with a nuanced answer: is cholesterol good or bad for you. Cholesterol is essential for human biology, yet it also contributes to a

Authors: Addison Davis & Annabella Irani Fey Mentor: Katherine Ferris. Katherine is a doctoral candidate in the Department of Oncology at the University of Oxford. Abstract Cancer remains one of the most widespread diseases globally, driven by genetic mutations that disrupt normal cell regulation, leading to uncontrolled proliferation and, in some cases, metastasis. While the immune system plays a crucial role in detecting and eliminating cancerous cells, tumors have evolved

Authors: Anushka Gundluru, Annabella Irani Fey, Harini Sivanandh Ramadass, Alice Sullivan, & Aryk Tyagi Mentor: Fiona Hartley, Fiona is currently a doctoral candidate in the Department of Oncology at the University of Oxford. Abstract This review paper examines the impact of big data on modern medicine, focusing on genomics, transcriptomics, metabolomics, and proteomics, which have advanced our understanding of biological processes and enabled personalized medicine. We revie

Authors: Sejal Pola, Harini Sivanandh Ramadass, Vishnupriya Ravindranath, Akanksha Saxena, & Iris Zheng Mentor: May Sin Ke. May is currently a doctoral candidate in the Department of Oncology at the University of Oxford. Abstract This review paper examines the current state of research on spinal cord injury (SCI), highlighting treatments such as corticosteroids, neuroprotective,  neuroregenerative therapies and scaffolding. With major parts of the demographic suffering from

Authors: Advik Chandok & Aiza Dada Mentor: Katherine Ferris. Katherine is a doctoral candidate in the Department of Oncology at the University of Oxford. Abstract Cancer grows more prevalent by the year, from 1.9 million new cases in the US in 2022 to over 2 million in 2023; despite this increase in cases, it is not met with a proportional increase in treatment progress, due not only to a lack of funding, but also a lack of success. This challenge can be attributed, in part,

Authors: Elianna Umana Kimura, Ethan Liu, & Adeline Sale Mentor: May Sin Ke. May is currently a doctoral candidate in the Department of Oncology at the University of Oxford. Abstract This review paper analyzes current research on type 2 diabetes, featuring treatments like antidiabetic medications, bariatric surgeries and sodium-glucose cotransporter-2 ( SGLT2) inhibitors. Considering the increasing number of citizens in the United States living with type 2 diabetes, it is of

Authors: Audrey Hu & Khushee Totla Mentor: May Sin Ke. May is currently a doctoral candidate in the Department of Oncology at the University of Oxford. Abstract This review paper explores recent advancements in therapies for spinal cord injury (SCI), focusing on its regenerative, neuroprotective and complementary approaches. Regenerative strategies, particularly stem-cell based therapies, offer avenues for restoring spinal cord function by differentiating into neural cells. N

Authors: Ava DeSanti, Josephine Grouette, Jordana Rosenberg, & Thelma Salinas Mentor: Fiona Hartley. Fiona is currently a doctoral student in the Department of Oncology at the University of Oxford. Abstract Gene therapy involves the manipulation of genetic material to rectify abnormal cellular processes, providing a selective and direct approach to targeting cancer cells. There are several types of gene therapy which aim to reduce cancer progression. Tumor suppressor gene th

Authors: Aadhitya Balaji, Maxence Lam, Nicholas Smemoe, & Ritvikka Sureshkumar Mentor: Danish Malik. Danish is currently a medical student at the University of Oxford. Abstract Type 2 diabetes exerts a considerable global health burden and is the most expensive chronic condition in the USA. Its management is multifaceted, with a mixture of pharmacological, lifestyle, and surgical interventions being used worldwide. This review paper compares the pharmacological and lifestyle